New clinical evidence shows that the DePuy Synthes ATTUNE® Knee System stands up to scrutiny in the form of registry data. Results compare favorably with the class of cemented total knee systems.
Global thought-leader surgeons, engineers, and experts in fields of study such as kinematics, anthropometrics, polyethylene wear and design collaborated to design and test the ATTUNE Knee System from Johnson and Johnson’s DePuy Synthes. Extensive research and science has gone into the design to help improve functional outcomes for patients, performance for surgeons, and efficiency for providers. This undoubted level of diligence in developing the system is supported by outcome and economic benefit assessment in a real world setting, as delivered by registry data.
New research from the National Joint Registry for England, Wales, Northern Ireland and the Isle of Man (NJR), which tracks and reports on the survivorship of implants, shows results for the performance of the ATTUNE Knee that compare favorably to the class of cemented total knee systems. In addition, an analysis of a large U.S. hospital administrative database indicates that ATTUNE Knee patients had 39% lower adjusted odds of discharge to a skilled nursing facility versus patients who received a total knee replacement with a leading competitive knee system.
The ATTUNE Knee System evidence generation program is the largest in DePuy Synthes’ history with multiple streams of ongoing data collection, both company and investigator initiated. Studies observe all four constructs in terms of survivorship, patient reported outcomes measures (PROMS), learning curve, and fluoroscopic kinematics studies. Radiostereometric Analysis (RSA) of implant micromotion is also being studied since it has been shown to be predictive of longer term survivorship. Together, these PROMS, kinematics, RSA studies, and survivorship data from national joint registries outside of the US provide a database of clinical performance of the ATTUNE Knee System.
The registry data shows the ATTUNE Knee yielding an estimated cumulative percent revision of 1.39% at 3 years (98.61% survivorship) for 4,463 knees, comparing favorably to the class of Cemented Total Knee Arthroplasty (TKA) that has an estimated cumulative percent revision of 1.50%.
Additional positive, interim results for the ATTUNE Knee were shared in three separate congress presentations at the recent International Society for Technology in Arthroplasty (ISTA) meeting in October 2016. One reported improved patient reported outcome measures compared to other leading knee systems. The second showed reduced incidence of symptomatic patellofemoral crepitus. The third presentation demonstrated patellofemoral biomechanics that emulated the functionality of a normal knee.
“In addition to survivorship and functional performance, recovery is also being studied. One short term study demonstrated improved patient outcomes as compared to another leading knee system, including less pain, better motion, and increased function. Another study showed shorter hospital length of stay, which has important implications for the care trajectory and costs”, said Dr. David Fisher, an orthopaedic surgeon at Ortho Indy in Indianapolis, IN. and a paid consultant of the company.
Source: DePuy Synthes