First U.S. Patient Benefits from Brainlab’s Automatic Brain Metastases Planning Software

Last week we covered J&J’s appearance at Eurospine 2015 during which the medtech giant spoke of its partnership with Brainlab in the delivery of holistic patient care. Now Brainlab itself tells us about the first U.S. patient to be treated with its new Automatic Brain Metastases Planning software.


Brainlab, headquartered in Munich, develops, manufactures and markets software-driven medical technology, enabling access to advanced, less invasive patient treatments. Using a unique dedicated algorithm, the company’s Automatic Brain Metastases Planning software allows delivery of highly conformal single-session treatments while helping to minimize dose spread to surrounding healthy tissue. By treating multiple brain metastases at one time, planning and treatment time can be significantly reduced, even with as many as 10 tumors to treat.

Brainlab’s new software has been used for the first time in the U.S. at Jefferson Hospital for Neuroscience in Philadelphia to deliver a tailored radiosurgery treatment to a patient with cancer that has metastasized to the brain. The procedure, in which all five of the patient’s brain metastases were treated, took less than 20 minutes, including setup time using the Brainlab technology. Using the traditional method, it could have taken three hours or roughly 30 minutes per tumor.

When treating such patients, Automatic Brain Metastases Planning offers improvements over the current standard of Whole Brain Radiation Therapy (WBRT) treatment. WBRT involves applying low doses of radiation to the entire brain over time and with many sessions, which can lead to cognitive deficits. Automatic Brain Metastases Planning software can automatically render a clinically ready treatment plan typically in less than two minutes.

Physician comments

“In our first patient treatment, we targeted five metastatic brain tumors in one frameless treatment session,” commented David W. Andrews, MD, Professor in the Department of Neurosurgery, Director of the Division of Neuro-oncologic Neurosurgery and Stereotactic Radiosurgery. “We will continue to use the Brainlab software with ExacTrac® patient positioning and monitoring to efficiently and effectively treat up to 10 metastatic tumors at once, helping prevent unnecessary loss of brain function that can occur with whole brain radiation therapy, such as memory loss or other cognitive deficits.”

“With traditional stereotactic radiosurgery techniques, each metastasis is planned and treated individually, thereby increasing treatment time,” said Wenyin Shi, MD, PhD, Assistant Professor of Radiation Oncology, Medical Director of Radiation Oncology at Jefferson Hospital for Neurosciences, and Co-Director of the Jefferson Brain Tumor Program. “The Brainlab software allows us to deliver a conformal cranial SRS plan with time-efficient precision targeting of several metastases in a single session.”

“Patients with diseases that cause brain lesions often require multiple treatments that are lengthy and cause discomfort. We are enthusiastic about any advances in practice that can limit the time a patient needs to undergo treatment and minimalize distress,” added Dr. Andrews.

Company comments

“As the first hospital in the U.S. to utilize Automatic Brain Metastases Planning for treatment, Jefferson Hospital for Neuroscience continues to demonstrate its commitment to advancing the treatment of multiple brain metastases,” said Sean Clark, President at Brainlab, Inc. “As industry thought leaders, Jefferson understands that this technology offers great advantages for patients, contributing to the overall progress of stereotactic radiosurgery.”

Source: Business Wire

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