Point of Care Flu Diagnosis Prototype Device Completed

UK-based  diagnostic device specialist OJ Bio reports successful completion of prototype development of a new wireless point of care (POC) diagnosis system that accurately and quickly identifies the presence of various disease types in a range of patient samples.

Background

The successful development of new platform technology for the rapid POC diagnosis of flu and other respiratory conditions has widespread potential for the detection of a wide range of other infectious diseases. The innovative hand held technology developed by OJ Bio combines new test assays carried on a multichannel biochip with a specialist reading device and supporting diagnostic software that can be carried on a mobile app, PC or the device itself. Importantly, the diagnostic device can be used at a patient’s bedside or other point of care location, such as a GP surgery or pharmacy, with the results being available immediately and without samples being sent for laboratory analysis. This capability also enables the device to be used in the patient’s home. The state of the art biosensors at the heart of the OJ Bio system brings together advanced technology from the company’s two parent organisations – Japan Radio Company (JRC) and Orla Protein Technologies. JRC has developed Surface Acoustic Wave (SAW) electronic chips which are coated with disease-specific biocapture surfaces developed by Orla. When biological samples, from serum, urine, saliva or blood, are applied to the biochip (held in a disposable cartridge), the presence of a disease antigen causes a shift in the phase angle of the surface acoustic wave passing across the chip surface and this is translated into an electronic signal. This signal can then be detected and its presence (or absence) determined, providing an unequivocal pass or fail result for the particular disease being tested for. Bluetooth connection of the reading device to special diagnostic software enables the test results to be displayed within seconds.   What happens next is that formal clinical trials using the device to detect a number of respiratory viruses are planned to begin in early 2015.

Company comments

Dale Athey, chief executive of OJ Bio, said: “Our new device provides a low cost test that dramatically improves the speed of diagnosis and treatment that should hit the disease at source and limit its ability to spread. However, the flexibility of the technology platform has wide ranging diagnostic testing potential, not only for the detection of human medical infections and conditions, but also for use in animal testing by veterinary practices. Recent progress has enabled us to accelerate the development of our system and projects are underway with partners in several market sectors which involve the use of the technology in a wide range of medical applications.” Source: OJ Bio 

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